Quantitative blood metabolomics · Hong Kong

Metabolomics studies you can stand behind.

Quantitative blood metabolomics, from study design to report.

Quality control · one batchSchematic
Schematic of quality control in one batchStudy samples in run order, with pooled QC samples at fixed intervals and reference serum. The raw QC signal drifts across the run; after correction it stays near 1.0. Schematic, not study data. QC signal, relative Injection order → 1.0 0.9 0.8 raw corrected
View readable QC schematic
Schematic of quality control in one batchStudy samples in run order, with pooled QC samples at fixed intervals and reference serum. The raw QC signal drifts across the run; after correction it stays near 1.0. Schematic, not study data. QC signal, relative Injection order → 1.0 0.9 0.8 raw corrected
Study samplePooled QCReference serumRawCorrectedIllustration only: as samples run in order, the raw QC signal drifts; the corrected example stays near a relative value of 1.0. Not study data. Controls and criteria are agreed per study.
Up to 324

metabolites quantified in absolute concentrations by Q300

Anal Chem 2021
About 100

published studies by other groups have used Q300

Europe PMC · 13 Oct 2026
1,234

liver-disease serum samples in the method's published validation

Anal Chem 2021

How a study runs

From question to report.

Study · step by stepSchematic
CasesControlsagesexBMImedicationSample size checked before any measurement
Retention time →Targeted LC-MS/MS · absolute quantitation
Pooled QC through the runrawdrift-correctedPrecision reported for every metabolite
Study reportMethodsQuality controlResultsLimits
01

Plan

Question, groups, covariates and sample size, agreed before a single sample is measured.

02

Measure

Targeted LC-MS/MS with absolute quantitation on Q300.

03

Control

Agree the controls, reference materials, drift checks and exclusion rules for each study.

04

Report

Results, methods and limits, written so a reviewer can check every step.

Our approach

Rigour you can check.

01

A published method

Targeted LC-MS/MS with absolute quantitation, described in Analytical Chemistry.

02

A defined QC plan

Agree batch controls and reference materials before measurement; report quality checks metabolite by metabolite.

03

Limits stated

Research use only. No diagnosis, no risk scores, no claim beyond the data.

Tell us about your study.

A short description is enough to start.